SennaSenna is an herbal stimulant laxative with serious risks, especially to the liver. Using senna to treat chronic constipation can lead to hepatitis, which is an extremely damaging condition to the liver that can lead to death.   The Department of Nephrology at Université catholique de Louvain in Brussels Belgium reported a case of a woman who had developed liver failure from ingesting an herbal tea containing senna. Her liver damage was serious enough that transplantation was considered. Researchers warned that liver damage is a risk of using laxatives containing senna, especially in excess. 
Cascara SagradaCascara sagrada, is an herbal stimulant laxative and, like senna, using it can lead to hepatitis. Multiple incidences have been reported of patients who developed serious hepatitis and liver failure after taking herbal products containing cascara sagrada.  The Division of Gastroenterology at Texas Tech University's Health Science Center warns that the reason cascara sagrada has been linked to hepatitis is because it contains a compound called anthracene glycoside, which has long been known to cause hepatitis. 
Perhaps the most common herbal laxative ingredient is psyllium. Psyllium is the seed of plantago ovata and psyllium husk is a main component of bulk laxatives. When psyllium husk meets water, it swells up like a sponge and stimulates bowel contractions. However, studies and documented cases of emergency medical situations have shown that psyllium is NOT a harmless or benign ingredient.Like peanuts, psyllium is a food allergen and allergic reactions from handling psyllium have been reported since 1970. Most notably, anaphylaxis. Anaphylaxis is a serious condition that involves respiratory tract irritation and swelling to the point of being unable to breath, which is incredibly scary because anaphylaxis can progress from bad to worse in a matter of seconds. If you're not prepared for an attack, you may find yourself unable to breathe and in real danger. The Oregon Health and Sciences University in Portland reported an incidence of psyllium sensitivity that resulted in death by way of anaphylactic shock.  The Department of Internal Medicine at Johns Hopkins University School of Medicine reported a separate instance of a patient who had experienced rhinitis and asthma due to psyllium exposure. The severity of her symptoms progressed to a life-threatening confrontation with anaphylaxis. The doctors warned that psyllium allergies are more common than most people appreciate In other words, don't think it can't happen to you. 
The Safe Alternative to Dangerous Herbal Colon CleansersThere's no need to risk your health on dangerous herbal laxatives when far, far more gentle and safe options are available. If you need relief from constipation, or a body cleanse in general, I recommend an oxygen based colon cleanser such as Oxy-Powder. Oxy-Powder does NOT carry the side effects that accompany toxic, herbal laxatives.
- Sonmez A, Yilmaz MI, Mas R, Ozcan A, Celasun B, Dogru T, Taslipinar A, Kocar IH. Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation. Acta Gastroenterol Belg. 2005 Jul-Sep;68(3):385-7.
- Beuers U, Spengler U, Pape GR. Hepatitis after chronic abuse of senna. Lancet. 1991 Feb 9;337(8737):372-3.
- Vanderperren B, Rizzo M, Angenot L, Haufroid V, Jadoul M, Hantson P. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother. 2005 Jul-Aug;39(7-8):1353-7. Epub 2005 Jun 14.
- Jacobsen C, Semb S, Kromann-Andersen H. [Toxic hepatitis following consumption of the herbal medicinal product Cascara Sagrada]. Ugeskr Laeger. 2009 Nov 9;171(46):3367-9. Danish.
- Nadir A, Reddy D, Van Thiel DH. Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity. Am J Gastroenterol. 2000 Dec;95(12):3634-7.
- Khalili B, Bardana EJ Jr, Yunginger JW. Psyllium-associated anaphylaxis and death: a case report and review of the literature. Ann Allergy Asthma Immunol. 2003 Dec;91(6):579-84. Review.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF Jr. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy. 1996 Apr;51(4):266-8.
†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. Global Healing Center does not dispense medical advice, prescribe, or diagnose illness. The views and nutritional advice expressed by Global Healing Center are not intended to be a substitute for conventional medical service. If you have a severe medical condition or health concern, see your physician.