Many indigenous cultures have used herbs and plants in therapeutic capacities to address health issues. This is a tradition and practice that extends to nearly every continent and includes nearly every culture and gives new meaning to “living off the land.” Fortunately, in spite of the advertising and brainwashing initiatives by the pharmaceutical industry, this habit has also taken root in America and over half the population uses some form of herbal therapy. Do you favor herbal remedies and suffer from poor circulation or other vascular conditions? You may be interested to learn about horse chestnut, or aesculus hippocastanum, a tree which contains compounds that may offer relief.
What is Horse Chestnut?
Horse chestnut is a tree native to the Balkan Peninsula but found throughout the northern hemisphere. Horse chestnut seeds, leaves, bark, and flowers have been used for centuries to help relieve an array of health problems. Horse chestnut seed has a place in European phytotherapy and is used to address vascular issues. A tea made from horse chestnut is a staple of Turkish folk medicine and used to relieve an upset stomach and pass kidney stones; they also use the seeds to alleviate hemorrhoid symptoms.  Today, horse chestnut is primarily used as a traditional remedy for vascular problems like chronic venous insufficiency, or CVI, a condition in which the veins do not efficiently return blood from the legs to the heart.
Why is Horse Chestnut Effective?
Horse chestnut contains a compound called aescin which has several observed prospective benefits. Research out of China suggests that aescin is resistant to systemic redness. It’s not uncommon for some compounds to temper redness by suppressing the immune system, since it can be a response from the immune system. Aescin resists redness and swelling without being immunosuppressive.  Aescin has also exhibited very strong antioxidant activity. Middlesex University in England published information that showed horse chestnut extract to be one of the most effective free radical fighters available. Additionally, Aescin is also a saponin, which is a word you may have heard before in conjunction with natural soap products. More than providing a natural clean, saponins also help the vascular system by making capillaries less fragile. This is likely to be of tremendous interest to persons who experience the swelling that results when fragile capillaries leak fluid. 
Horse Chestnut and Vein Health
CVI is a condition in which ill-functioning valves prevent blood from efficiently circulating away from the extremities. There are different causes of CVI but the most common include deep vein thrombosis and obesity. CVI is often identifiable by itchiness, increased leg pigmentation, swelling, varicose veins, and even ulcers. The most common treatment is to wear compression socks. Made of a tight elastic, compression socks do exactly as their name implies, they compress the veins and arteries which decreases the size of distended veins. This increases pressure on the arteries and forces more blood to circulate. All this allows less blood to pool in the feet and legs.
Studies have shown that horse chestnut extract provides a similar effect to compression socks and helps to contract veins and arteries.  According to the Journal of the Norwegian Medical Association, horse chestnut seed extract is widely used throughout Europe for chronic venous insufficiency (CVI).  Italy’s University of Milano performed research that showed aescin to be as effective as compression therapy for CVI and, additionally, aescin is significant for not just CVI, but also hemorrhoids and edema.  Why? At the lowest level, horse chestnut seed extract is thought to inhibit the breakdown of capillary wall proteins. 
Horse Chestnut Research
The Institute of Medical Biometry and Medical Informatics at Germany’s University of Exeter reviewed available information and found that while traditional CVI treatment consists of compression therapy, compression therapy can be painful and susceptible to compliance issues. In these instances, oral medications may provide the most promising outlook and the positivity of that scenario increases when the medications are from natural, plant sources like horse chestnut. In their review, researchers were quick to note that the symptoms of CVI improved when an extract of horse chestnut was used. 
Another German study involved 22 patients with CVI who were given capsules with either an aescin extract or a placebo. Those who took the asescin extract noted a “compression like” effect in the form of decreased intravascular volume; supporting the argument for horse chestnut’s benefit for venous problems in the legs. 
The University of Oklahoma Health Sciences Center evaluated various approaches to dealing with vein and circulation problems. Compression therapy and topical creams have been shown to reduce pain and swelling but their long term application and benefit is questionable. Obviously, the best long term solution is to address potential causes at the root, especially if obesity or type 2 diabetes are a factor. Absent that, researchers noted that herbal supplements like horse chestnut may have much to offer for improving symptoms of CVI. 
Supplementing with Horse Chestnut
The research into horse chestnut benefits has, fortunately, observed very few adverse side effects. To the contrary, horse chestnut is thought to be remarkably safe and well tolerated by most people. Some research has shown that aescin is more absorbable by the body during the daytime than night- something to consider if you supplement with horse chestnut. 
If circulation and vein health are a concern in your life, I encourage you to take inventory of yourself and determine if there are any factors you can change to get those issues under better control. Are you eating healthy? Are you exercising enough? Would losing a few pounds put you in a better spot? When was the last time you cleansed your body? Sometimes those are factors, sometimes they’re not. Regardless, if lifestyle choices aren’t putting you where you want to be, Hematrex® contains organic horse chestnut and is the only vein and circulatory support supplement I recommend.
- Küçükkurt I, Ince S, Keleş H, Akkol EK, Avci G, Yeşilada E, Bacak E. Beneficial effects of Aesculus hippocastanum L. seed extract on the body's own antioxidant defense system on subacute administration. J Ethnopharmacol. 2010 May 4;129(1):18-22. doi: 10.1016/j.jep.2010.02.017. Epub 2010 Feb 26.
- Wang T, Fu F, Zhang L, Han B, Zhu M, Zhang X. Effects of escin on acute inflammation and the immune system in mice. Pharmacol Rep. 2009 Jul-Aug;61(4):697-704.
- Wilkinson JA, Brown AM. Horse Chestnut - Aesculus Hippocastanum: Potential Applications in Cosmetic Skin-care Products. Int J Cosmet Sci. 1999 Dec;21(6):437-47. doi: 10.1046/j.1467-2494.1999.234192.x.
- Felixsson E, Persson IA, Eriksson AC, Persson K. Horse chestnut extract contracts bovine vessels and affects human platelet aggregation through 5-HT(2A) receptors: an in vitro study. Phytother Res. 2010 Sep;24(9):1297-301. doi: 10.1002/ptr.3103.
- Methlie CB, Schjøtt J. [Horse chestnut--remedy for chronic venous insufficiency]. Tidsskr Nor Laegeforen. 2009 Feb 26;129(5):420-2. doi: 10.4045/tidsskr.09.33871. Norwegian.
- Sirtori CR. Aescin: pharmacology, pharmacokinetics and therapeutic profile. Pharmacol Res. 2001 Sep;44(3):183-93. Review.
- Suter A, Bommer S, Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. Adv Ther. 2006 Jan-Feb;23(1):179-90.
- Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;11:CD003230. doi: 10.1002/14651858.CD003230.pub4.
- Bisler H, Pfeifer R, Klüken N, Pauschinger P. [Effects of horse-chestnut seed extract on transcapillary filtration in chronic venous insufficiency]. Dtsch Med Wochenschr. 1986 Aug 29;111(35):1321-9. German.
- Rathbun SW, Kirkpatrick AC. Treatment of chronic venous insufficiency. Curr Treat Options Cardiovasc Med. 2007 Apr;9(2):115-26.
- Bässler D, Okpanyi S, Schrödter A, Loew D, Schürer M, Schulz HU. Bioavailability of beta-aescin from horse chestnut seed extract: comparative clinical studies of two Galenic formulations. Adv Ther. 2003 Sep-Oct;20(5):295-304.
†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. Global Healing Center does not dispense medical advice, prescribe, or diagnose illness. The views and nutritional advice expressed by Global Healing Center are not intended to be a substitute for conventional medical service. If you have a severe medical condition or health concern, see your physician.