The Health Benefits of Calcium Orotate

by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM Published on , Last Updated on

The human body has a need for calcium. Calcium enables us to have strong bones and prevents bone loss diseases such as osteoporosis. The effects of depleted calcium levels span far beyond the scope of weakened bones.

Studies done at the Osteoporosis Research Center at Creighton University found that calcium plays a major role in many bodily functions. Unfortunately, estimates from federal health statistics show that only 20% of Americans are getting the levels of calcium required for proper body function. This deficiency can have resounding effects as calcium is particularly important for the heart and the circulatory system.

Research shows that calcium can also aid in the prevention of weight gain, as well as the maintenance of healthy weight levels. When the body does not receive enough calcium, it enters emergency starvation mode, and begins to leach calcium into the bloodstream. The hormones involved in stimulating this response (parathyroid hormone and calcitriol) are also responsible for stimulating and storing fat cells.

Adequate amounts of calcium provide for healthy hair, nails and teeth. Without enough dietary calcium, the body extracts it from the bones. Good levels of calcium in the body are important at all ages, whether it be growing children or the elderly at risk for osteoporosis.

Supplementing With Calcium

Calcium orotate is the single most effective form of calcium supplement. Extensive research done by Hans A. Nieper, M.D. has shown that orotates penetrate cell membranes, enabling the effective delivery of the calcium ion to the inner-most layers of the cellular mitochondria and nucleus.

Other forms of calcium supplements, such as calcium carbonates, citrates, gluconates, lactates, malates and phosphates, do not have the ability to penetrate deep into the membranes.

Dr. Nieper found calcium orotate could help with:

  • IBS
  • Colitis
  • Hepatits
  • Bursitis
  • Diverticulitis
  • Multiple sclerosis
  • General bone reduction
  • Arthritis
  • Retinitis
  • Sinusitis
  • Psoriasis
  • Vaginitis
  • Gastritis
  • Laryngitis
  • Tendonitis
  • Elevated blood pressure
  • Discomfort due to bone irritation
  • Osteoporosis
  • Pancreatitis
  • Encephalitis
  • Shin splints

Calcium Orotate and Bone Strength

It has been well established that calcium supplements can work as preventative measures against bone loss and osteoporosis. While many forms of calcium supplement may aid in the prevention of this loss, Hans A. Nieper’s studies showed that calcium orotate gave the bones more usable calcium per milligram consumed.

Calcium Orotate and Weight Control

Calcium orotate was also shown to reduce food cravings. Nieper’s studies found that by supplementing the diets of chronic over eaters with calcium orotate, cravings were reduced significantly.

Mood Enhancement

Calcium orotate has been linked to mood-enhancement and overall cognitive enhancement.

Heart Protection

Calcium aids cardiac muscles and assists the nervous system in keeping optimal pressure levels in the arteries.

Aids in Premenstrual Symptoms

Adequate amounts of calcium stop the release of hormones related to premenstrual mood-related disorder, including anxiety, depression and irritability.

Difference Between Calcium Orotate and Citrate

In the video below, I explain the difference between calcium orotate and calcium citrate.

†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. Global Healing Center does not dispense medical advice, prescribe, or diagnose illness. The views and nutritional advice expressed by Global Healing Center are not intended to be a substitute for conventional medical service. If you have a severe medical condition or health concern, see your physician.

  • Joseph Dubroff

    Calcium is very important for many reasons in the human body research clearly indicates that. Another consideration is the form the calcium comes as a salt. Calcium carbonate is a very popular form but has been shown to be less absorbable then other salts such as calcium malate and calcium citrate.

  • justin

    I’d refer everyone to Google search for info by David Wolfe on calcification and ‘bad calcium’.

    He brings to light new research that debunks what have turned out to be false assumptions on calcium supplements.

    Even such forms as ‘highly absorbable’ cal citrate have been shown to not be absorbed by the body but rather build up in the wrong places and cause things such as heart disease,arthritis,etc

  • Joint Pain Guy

    what about joint pain / joint cartiladge degeneration. You would think calcium, if anything, would stop the degeneration like glucosamine has been said to do.

    Pretty amazing that calcium can do all of that!

  • Kathryn


    I’m wondering what/where are your sources for calcium orotate? (Apologies, if I happened to miss that in your article!)


  • Louise

    Calcium orotate is definitely an effective way to get calcium into your system. Milk is totally overrated, since the increased protein load on the kidneys results in increased calcium secretion via the urine. More calcium is secreted than is absorbed by drinking milk. Why else is it that osteoporosis is at its highest levels ever?

  • shine

    with out the presence vit d3 how it is absorbed

  • TJ

    This information is very interesting. I didn’t know of such Calcium salt. I wonder if there is any scientific study that compares say, Calcium Carbonate, Calcium Citrate+Calcium Malate and Calcium Orotate bioavailability in a group of human subjects. Pubmed doesn’t give me any results.

    Frankly, from my current knowledge, I would rather use enteric coated calcium supplement like calcium supplement than changing to a new salt whose long term effects are not well established.

  • Debby Shapiro

    Hi Justin

    Interesting., will look up Wolfe reference, thanks. Doing research as felt unwell on a number of occasions this week and think it is because of taking ultimate bone support by solgar! Have low bone density so looking for alternatives. Have you tried the orotate mentionned on this site. Btw dried savory seems to be one of top foods with calcium!!

  • Abby

    What about bone meal micro crystalline hydoxyapatite? I called the company that makes my mom’s supplement (Bone-up) and they said it was bone meal. has vitamin C, K2, and some other things.

  • ghc_health

    Bone meal supplements were linked to toxic metal contamination in the 1980’s. Things may have changed since then but I couldn’t vouch for them. Regardless, bone meal is not vegetarian friendly.

  • OceanGram

    What brand do we buy..

  • ghc_health

    There are a few options but we recommend IntraCal. The quality of the ingredients is unparalleled and the manufacturing process is as controlled and well managed as can be. There may be other companies that also produce an acceptable product but I couldn’t tell you one.

  • dave234

    Does the orotate form help with tooth re-mineralization as well?

  • Edward Group

    It provides calcium and that’s part of the equation with promoting bone health, so it sounds reasonable enough. I can’t point you toward a study that confirms it, though.

  • Holly

    I read constantly about supplements, etc. in trying to help my osteoporosis. I wondered about your input on lactoferrin and a good vitamin D supplement. I’ve been taking an algae raw calcium supplement that sounds great but hasn’t produced results for me yet.

  • Vitamin D3 is the best vitamin D supplement. We have a vegan friendly version that’ll be released soon. Lactoferrin is an interesting supplement although I haven’t tried it myself.

  • Laci

    Will Calcium Orotate help diminish Cellulite like Glucosamine is said to do? I heard that Glucosamine is an affective cellulite treatment because it helps your body repair the dermis and connective tissue. I have found a supplement that is Glucosamine & Chondroitin with MSM. Though, I would prefer to find a supplement through Global Healing Center. I try to find any supplement that I can through you, because anything that I have taken that has been recommended by you has great results. I want to be able to trust what I put in my body. I have read that Glucosamine and Chondroitin can have ill affects on the body after a while, is this true? I am not sure what MSM is. I am 23 years old, and I already have cellulite. I know that it is difficult to reduce cellulite, but do you know of anything that may help? Thank you so much for your time and information.

  • That might be a stretch as calcium orotate isn’t the same thing as G&C. You can check out MSM in this article.

  • Lee

    In this case Orotate is the catalyst for the calcium and it’s is the finest of the catalysts as opposed to citrate or aspartate, although citrate and aspartate do the job as well. Daily Manufacturing (ph# 800-868-0700) makes an excellent product and they’ve been around for years. I have no connection whatsoever to them other than the fact that I’m a happy customer.

  • Pingback: Understanding Calcium: The Best Forms Of Calcium Supplements | | Quantum Reality()

  • Pingback: Understanding Calcium: The Best Forms Of Calcium Supplements - Alternative Report()

  • Teresa Sapphire Horner

    Please help something happened almost a year ago, just a light fall n wrong docs, but I got a broken tailbone that broke going up into pelvic, and fractured my hip and few months later my L5 is fractured and now L4 with bone spurs. Trying to get healthy and eliminating thing slowly, but would this product help somebody like me? I heard bone broth is good too but so desperate I know your a busy man but could you help me?

  • Pingback: What Are Micronutrients? A Review of Essential Nutrients - Alternative Report()

Top Selling Supplements

Colon Cleanser Oxy-Powder® is the top quality colon cleanser. Promotes optimal colon health and regular bowel activity. Learn More

Liver Cleanse Kit This complete liver cleansing kit is a comprehensive approach to cleansing your liver. Learn More

Get to know Dr. Group

  Our Company




  • Global Healing Center
    2040 North Loop West, Ste. 234
    Houston, Texas 77018
    Telephone: 713-476-0016
    Toll Free: 1-800-476-0016
  • Contact Us