What is Zinc Ororate?
Zinc orotate, used by Dr. Hans Nieper, is more neutrally charged than other forms of zinc, which allows the human body to receive the largest serving of zinc since it can pass seamlessly through the cell membrane.
What are the Benefits of Zinc Ororate?
All tissue and organs in the body require zinc and it is involved in numerous aspects of cellular metabolism and required for the catalytic activity of approximately 100 enzymes. However, the body has no specialized zinc storage system; daily intake is required to maintain a steady state.
- Counters the progression of macular degeneration
- Contains antioxidant properties
- Improves brain function
- Protects skin from UV light
- Reduces lead toxicity
- Improves testosterone levels
- Protects the liver from alcohol
- Fights viral infections
- Reduces tissue damage from diabetes
- Prevents osteoporosis due to zinc deficiency
- Improves healing of wounds
- Neutralizes free radicals
- Plays an important role in immune function and wound healing
- Assists with protein synthesis, DNA synthesis, and cell division
- Supports normal growth and development during pregnancy, childhood, and adolescence
- Is required for proper sense of taste and smell
How Common is Zinc Deficiency?
Estimates say that over one quarter of the world suffers from zinc deficiency. It occurs, even in industrialized countries, as the result of illness and diet. Symptoms can include diarrhea, skin rash/lesions, hair loss, night blindness, loss of smell or taste, memory loss, and, in extreme circumstances, even death.
A Brief History of the Invention of Zinc Orotate

Dr. Hans Nieper
Zinc Orotate was developed around Dr. Hans Nieper's groundbreaking research!
Dr. Hans Nieper, a physician and experimenter, believed minerals in an orotate form pass through cell membranes easily without breaking apart and reach the areas where it’s needed most. The unique molecular structure of zinc ororate is able to penetrate tissue to act as a superior mineral transporter.
Zinc orotate was made popular as a supplement by Dr. Hans Nieper. The innovative German physician considered orotates to be superior to other anions as bioavailability enhancers for minerals like zinc. His belief was that neutrally charged orotate salts could easily pass through cell membranes, transporting mineral atoms into cells and cultivating higher tissue concentrations.
Research from Dr. Nieper has shown that zinc orotate, when compared to other forms of zinc, are more neutrally charged, a process that allows the zinc to pass seamlessly through the cell membrane. This allows the human body to receive the largest doses of zinc.
Each bottle contains 100 tablets.
Ingredients:
- Vitamin E (compritol 888 and glyceryl behenate)
- Zinc Orotate (zinc)
Other Ingredients:
- Duratex
- Pure food glaze
- Plasdone
- Avicel
- Ac-Di-Sol
- Magnesium
Frequently Asked Questions About Zinc Ororate
- Is zinc an antioxidant?
- What is the recommended zinc serving?
- What effect does zinc have on lead toxicity?
- Does zinc affect fertility?
- How does zinc affect alcohol consumption?
- What relationship does zinc have with cardiovascular disease?
- What effect does zinc have on herpes outbreaks?
- Is zinc related to diabetes?
- What effect does zinc have on soreness, immunity, and aging?
- Can zinc help with osteoporosis?
- How is zinc beneficial for bone and joint problems?
- What effect does zinc have with macular degeneration?
- What role does zinc play with the brain?
Is zinc an antioxidant?
Zinc is a component of Superoxide dismutase (SOD), an enzyme and major antioxidant tool the body uses to neutralize free radicals. Its antioxidant properties may explain some of the effects it has on the body.
What is the recommended zinc serving?
For adults, the recommended zinc intake is 8 to 11 mg per day.
What effect does zinc have on lead toxicity?
Lead poisoning depletes the body of its supply of Superoxide Dismutase (SOD), an antioxidant enzyme. The results ofe xperiments with lead-exposed rats suggest that zinc supplementation revitalizes SOD to normal levels; it mitigates lead toxicity.
Does zinc affect fertility?
Studies show zinc, vitamin A, vitamin E, and selenium increase sperm production and promote testosterone synthesis.
How does zinc affect alcohol consumption?
Zinc orotate was shown in experiments with mice to protect the liver from large servings of ethyl alcohol. The effect is thought to involve the neutralization of free radicals in the liver tissues damaged by alcohol.
What relationship does zinc have with cardiovascular disease?
Cardiovascular disease is a condition where oxygen ions damage arteries and veins. The primary free radical responsible is superoxide. Cardiovascular conditions, such as hypertension, atherosclerosis, heart failure, and non-cardiovascular ailments, such as diabetes, sepsis, Alzheimer’s disease, and aging, increase superoxide levels in blood vessels.
Orotate has been shown to be effective for cardiovascular disease because it improves the energy status of injured heart tissue and also limits damage to the heart in the event of interrupted blood flow. It also improves the HDL/LDL ratio, decreases plaque formation, slows heart degeneration, and prevents congestive heart failure.
What effect does zinc have on herpes outbreaks?
Zinc may be useful for active herpes simplex outbreaks and preventing recurrences. Patients given oral zinc supplements in clinical studies saw, on average, 57% fewer days in which they experienced an outbreak. The serving was 139 mg per day of zinc sulfate, which is 316 mg per day of zinc orotate. However, in order to provide better bioavailability, a smaller serving of zinc should be used.
Is zinc related to diabetes?
Diabetes causes systemic oxidative stress and is often accompanied by zinc deficiency, which increases the susceptibility of the heart to oxidative damage. There is good reason to consider zinc supplementation to prevent or delay diabetic cardiomyopathy; a 2003 Tunisian study showed a 15% reduction in oxidative stress with six months of zinc supplementation.
What effect does zinc have on soreness, immunity, and aging?
Zinc deficiency is observed in chronic illness, injury, and age-related soreness. Because zinc is resistant to soreness, a cycle occurs where chronic redness depletes zinc and then the zinc deficiency allows the swelling to continue.
Zinc and vitamin C are important for immune function and in defending against infectious agents. Adequate intake of vitamin C and zinc lessens the risk, severity, and duration of colds, pneumonia, respiratory tract infections, and other infectious diseases.
Can zinc help with osteoporosis?
Although zinc deficiency plays a role in causing osteoporosis, it is not understood why. Dietary zinc supplementation may make sense as a preventative measure.
How is zinc beneficial for bone and joint problems?
Cartilage in the joints depends upon the allocation of glucose, amino acids, vitamins, and essential trace elements. A University of Liverpool research group found that, “… dietary supplementation programs and nutraceuticals used in conjunction with NSAIDS may offer significant benefits to patients with joint disorders, such as OA [osteoarthritis] …"
What effect does zinc have with macular degeneration?
Age-related macular degeneration (AMD) is a retinal disease common in the elderly that leads to vision loss and legal blindness. Supplementation with antioxidants (zinc, vitamins C and E, lutein and zeaxanthin — two antioxidants specifically found in the retina) may be a preventive measure. A clinical trial (AREDS in the USA) discovered zinc, betacarotene, and vitamin C supplements to be beneficial against the progression of advanced age-related macular degeneration.
What role does zinc play with the brain?
Roughly 10% of the zinc in the brain serves as a modulator of information transfer between nerve cells. Zinc deficiency is attributed to learning impairment and olfactory dysfunction; it may also increase the brain’s vulnerability to epileptic seizures.
Suggested Use
With meals, take 1 tablet twice a day or as directed by a healthcare professional.
Warnings
- If you are currently pregnant or nursing, consult with your physician before using a zinc supplement.
- Consult your pediatrician before giving children a zinc supplement.







