The Liver and Liverstones

by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM Published on , Last Updated on March 24, 2015

liver stones

Each year, millions of people in the United States suffer from gallstone-related pain. However, it may surprise many of these individuals to discover they are, in fact, suffering from the presence of liver stones. Liver stones are the less publicized cousins of the gallstone, as the two are essentially the same. Ultimately, location defines the difference between the two. To help reduce the risk of suffering from this painful condition, everyone should understand how the liver functions and what can be done to support its health.

The Location and Purpose of the Liver

The liver is the largest gland in the body and it’s located at the beginning of the small intestine. The gallbladder, for comparison, is located behind the liver, near its base. The main purpose of the liver is to produce bile, which is an essential secretion for breaking down digested lipids into smaller particles so fats and fat-soluble vitamins can be absorbed by the small intestine.

The liver forms bile from water, electrolytes, and other molecules including cholesterol, bilirubin, bile acids, and phospholipids. Adults produce between 400 and 800 ml of bile each day and it’s stored in the gallbladder until needed. [1] Besides manufacturing bile, the liver works as a filter to detoxify and purge harmful chemicals (such as alcohol) from the body.

What are Liver Stones?

Liver stones are commonly formed whenever an excess of cholesterol exists in the body. When excess dietary cholesterol is present, the remainder often crystallizes into small, pebble-shaped masses. Recently, researchers at the University of Bonn in Germany discovered that heredity may also be a contributor to the condition. The scientists believe they have isolated a gene within the body that greatly increases a person’s chances of forming liver and/or gallstones. [2]

General Statistics about Liver Problems

  • Physical injuries to the liver are responsible for just 5% of all hospital admissions. [8]
  • 80% of all cases of liver toxicity are caused by pharmacological drug reactions. [9]
  • More than 900 prescription drugs are known to cause injury to the liver. Toxicity is the leading reason for withdrawing a drug from the market. [10]
  • Liver and gallstones are present in 10 % to 20% of the population. [11]

9 Herbs That Promote Liver Cleansing

The top nine herbs that promote liver cleansing include:

  • Chicory root
  • Dandelion leaf
  • Dandelion root
  • Greater celandine
  • Milk thistle seed
  • Peppermint leaf
  • Turmeric
  • Yellow dock root
  • Chanca piedra

For a more detailed list of the top 9 herbs for liver cleansing, click here.

4 Common Diseases of the Liver

Due to the liver’s role as the body’s detoxifying system, much of what we eat and drink can greatly affect its health. Here are some of the more common diseases of the liver:

1. Cirrhosis

Damage to the liver causes scarring which further prevents the liver from functioning the way it should. Common causes of cirrhosis include alcoholism and hepatitis. About 5% of cirrhosis patients develop liver cancer and end up receiving liver transplants due to excessive scarring.

2. Fatty Liver

“Fatty liver” is a common condition in people who drink too much alcohol. The liver becomes enlarged by the accumulation of fat cells. Usually, the only symptom presented is a slight discomfort within the abdomen. The condition normally improves if the person in question ceases drinking alcohol.

In addition to alcohol-induced fatty liver, there is also non-alcoholic fatty liver disease that typically presents the exact same symptoms but without alcohol as the cause. Non-alcoholic fatty liver disease is often related to insulin resistance (type 2 diabetes) and obesity, so weight loss and managing carbohydrate intake may be helpful.

3. Hepatitis

Alcoholic hepatitis (liver inflammation) is also caused by the intake of too much alcohol and is often a precursor to cirrhosis and eventual liver failure. If detected early enough, damage to the liver may be somewhat reversed. Viral Hepatitis, on the other hand, attacks the liver directly. Actually five different types of viral Hepatitis exist:

  1. Hepatitis A (HAV) – Can affect anyone and ranges from single cases to widespread epidemics
  2. Hepatitis B (HBV) – A deadly disease causing cirrhosis, cancer, liver failure, and even death
  3. Hepatitis C (HCV) – Easily spread by coming into contact with the blood of an infected person
  4. Hepatitis D (HDV) – A virus found in the blood of affected individuals, and the patient usually has HBV as well
  5. Hepatitis E (HEV) – Similar to HAV, but rarely found in the United States.[3]

4. Gilbert Syndrome

Gilbert Syndrome is caused by a defect in the uptake of bilirubin into the liver cells. Gilbert Syndrome can be very difficult to identify and is sometimes confused with liver disease.

Symptoms of a Sluggish Liver

When your liver isn’t functioning at peak performance, you may experience some or all of the following symptoms:

  • Chronic Fatigue
  • Depression
  • Digestive Difficulties
  • Chemical Sensitivities

It’s interesting that the symptoms for impaired hepatic detoxification are commonly the same as those attributed to patients suffering from exposure to toxic chemicals.

Can Any Organisms Harm the Liver?

Yes! Liver flukes (Trematodes) are a type of flatworm which infects the digestive system and other organs in the body. Adult flukes have external suckers which allow it to attach and leech nourishment. Trematodes normally enter the body through the act of eating uncooked fish or plants and fish from fluke-infested waters. Trichinosis is another type of parasitic disease that can harm the liver. Trichinosis is contracted from eating under-cooked meat (usually pork) and it affects the bile ducts that drain the liver.

A condition known as schistosomiasis occurs when parasites enter the body through the skin, usually from walking barefoot in infested fresh water. The organisms travel through the body, settling in the small veins of the liver. Ultimately, schistosomiasis results in cirrhosis of the liver due to the scarring caused by the inflammation. Also, many people may not realize Hepatitis A is a virus that enters the liver as an organism. The most common way to contract Hepatitis A is to eat food prepared or handled by someone who didn’t thoroughly wash their hands after using the bathroom.

What Chemicals Affect the Liver?

Chemicals which can cause hepatotoxicity include Acetaminophen, Isoniazid, aflatoxins, arsenic, and carbon tetrachloride. [4] Taking more than the recommended amount of Acetaminophen causes the glutathione pathway to become overwhelmed with NAPQI—Acetaminophen’s metabolite. Ultimately, this toxic compound accumulates in the liver and the glutathione is unable to remove it, thus damaging the liver in the process.

Used to treat Tuberculosis, Isoniazid is a powerful medication necessitating the patient to undergo constant liver tests. Isoniazid is believed to cause granulomas (chronic inflammatory nodules) within the liver.

Aflatoxins occur naturally and can be found in soil, decaying vegetation, and other natural settings. [5] Aflatoxins typically flourish in areas of high heat and moisture and normally contaminate crops of cereals, spices, peanuts, and other dried goods. High exposure to aflatoxins causes carcinoma, cirrhosis, and eventual necrosis of the liver.

Arsenic is a well-known carcinogen and teratogen. The most common exposure for humans comes from drinking tap water. High levels of arsenic can be fatal within 12-48 hours after ingestion with some deaths occurring within one hour. [6] Once absorbed into the body, arsenic is stored in the liver where it can contribute to the onset of cancer.

Carbon tetrachloride is very dangerous to humans and animals when inhaled. Clinical signs of carbon tetrachloride inhalation include elevated levels of the hepatic enzyme Aspartate Aminotransferase, elevated levels of bilirubin, decreased levels of albumin and fibrinogen, and a swollen and tender liver. [7]

What Diet Promotes A Strong Liver?

Besides the intake of pharmaceutical drugs, a poor diet is a major contributor to most liver problems. High alcohol intake is the most common form of dietary danger to the liver. However, you can improve your diet a number of ways to promote overall liver function.

  • A diet too high in protein may cause a condition called hepatic encephalopathy or “mental confusion”. While the exact cause of hepatic encephalopathy is still unknown, it is theorized that when the body digests high amounts of proteins, excessive ammonia is formed, which affects the central nervous system.13 Your doctor should always be consulted before altering the protein in your diet.
  • A diet high in calories, especially carbohydrates and trans and saturated fats, can equally result in liver problems. Excess caloric intake can lead to fatty deposits within the liver.
  • Watch your Vitamin A intake, as it is high in saturated fat and cholesterol and can be very toxic to the liver when taken in large amounts. However, Emulsified Vitamin A does not contain fat or cholesterol. Emulsified Vitamin A is a liquid form of the vitamin that is derived from the carotene found in green and yellow vegetables and egg yolk. Emulsified Vitamin A is a powerful antioxidant for supplementing your diet. Vitamin A also helps promote cell differentiation and supports the body’s normal immune system response.

The best diet for the liver is one low in protein and also sodium.14 Eating plenty of raw fruits and vegetables will help to keep your body, especially your liver from overtaxing itself. Approximately 30% to 40% of your diet should consist of dark green leafy vegetables and orange, red, purple, and yellow colored fruits and vegetables. A diet high in trans and saturated fats causes the liver to work extra hard, so reducing your intake of those fats is critical to a healthy liver.

Avocados and oily fish such as salmon, tuna, and sardines are excellent choices for promoting liver health. Many varieties of raw seeds such as flaxseed, sunflower, and alfalfa seeds are beneficial in this regard as well. Certain oils (primrose, black currant seed, and cold-pressed olive oil to name a few) assist the liver as well.

Choosing a Liver Cleansing Supplement

Along with a healthy and cleansing diet, you must routinely cleanse your liver to promote optimum function and health. A number of liver and even gallbladder cleansing products can be found in health stores and on the Internet, but the most effective of these are manufactured with only 100% organic and wildcrafted herbs and are produced using proprietary or Instruct® processes.

Liver cleansers produced with these methods, such as Livatrex™, provide you with herbs extracted using pure Kosher-certified vegetable glycerin rather than alcohol, thus making them the safest and most effective class of supplements for supporting your health improvement initiatives.


  1. Bowen, R. Secretion of Bile and the Role of Bile Acids In Digestion. Online. (last accessed: 2007 October 4).
  2. Lammert, F., Grunhage, F., Walier, M. and T. Wienker. Research team discovers gallstone gene. Hepatology. Issue 46. Pub. 2007 July 11. (last accessed: 4 Oct 2007).
  3. Centers for Disease Control and Prevention. Viral Hepatitus. (last accessed: 2007 October 5).
  4. Lawrence S. Friedman MD, Emmet B. Keeffe MD. Handbook of liver disease: expert consult. Elsevier Saunders. 2011 August 26. ISBN-10: 143771725X. Print.
  5. Waliyar, Dr. F. Principal scientist (Pathology) and managing director for agri-science park. (last accessed: 2007 October 17).
  6. PDR Health. Arsenic. 2007.
  7. Department of Health and Human Services. ATSDR. (last accessed: 2007 October 17).
  8. Peter R. McNally DO FACP FACG. GI/Liver secrets plus. Mosby Inc. 2010 April 2. IDBN-13: 978-0323063975. Print.
  9. Pirmohamed M, Breckenridge AM, Kitteringham NR, Park BK. Adverse drug reactions. BMJ. 1998 Apr 25;316(7140):1295-8. Review.
  10. Scott L. Friedman, James H. Grendell, Kenneth R. McQuaid. Current diagnosis and treatment in gastroenterology. Lange Medical Books/McGraw-Hill Pub. Division. 2003. ISBN:0-8385-1551-7. Print.
  11. Virtual Medical Centre. Gallstones. 2003 September 21.

  • Dr.Pearl

    Just because the article said “Excess caloric intake CAN lead to fatty deposits within the liver” doesn’t mean it was the cause for you. Every body is different. What’s the cause for one person, may not be the cause for another.

  • Janeen

    Contradictory statements here. Reduce your fat intake for a healthy liver, but eat all these fats for a healthy liver. ?

    “A high fat diet causes the liver to work extra hard, so reducing your fat intake is critical to a healthy liver.”

    “Avocados and oily fish such as salmon, tuna, and sardines are excellent choices for promoting liver health. Many varieties of raw seeds such as flaxseed, sunflower, and alfalfa seeds are beneficial in this regard as well. Certain oils (primrose, black currant seed, and cold-pressed olive oil to name a few) assist the liver as well.”

  • ghc_health

    Thank you both for sharing — everyone’s body is different and individual results do vary, but it’s important to have some baselines to keep in mind!


    I’m guessing he means trans-fats, but a clarification would be nice.

  • Stephanie Stuart

    Pretty ostentatious for you to tell a Dr what is not true within his expertise field. Your advice to eat as many calories as you feel like completely floors me.

  • Mark Cooper

    Dr. Group…..Man….You just plain ROCK! Thank you for sharing your knowledge with us.Your EXCELLENT products are so appreciated in a sea of bogus and inferior TOXIC METAL containing herbal products. You sold me with the Oxy Powder and now the Liver Cleanse has made me a fan for life…..Literally.

  • Global Healing Center

    Right on, Mark. Thanks for the kind words!

  • Mark Cooper

    I’m serious too. I’m doing your 9 step cleanse and just completed my first liver cleanse and….well…..Let’s just say it was successful. :-) I can see myself doing the 9 step cleanse every four months. Your book is AMAZING too! I’m a 46 year old man with RA and, through a COMPLETE lifestyle change, I am off ALL medications and coming alive….Truly alive. And your protocol and products are key to my continued success. Now….Right another book!!!! :-) Love watching you on Alex Jones and with Mike Adams. Sorry to write a novel here…I’m just very excited to have found you and your excellent products and info. God bless and be well. :-)

  • Global Healing Center

    That’s awesome, Mark, please be sure to leave a review and let us know how you feel after the cleansing!!

  • Mark Cooper

    I will. I’ll tell you right now….I completed the Liver cleanse yesterday and my energy is high….And last night I slept a full 8 hours (9:30pm to 5:30am) and, for me…That’s unheard of. Thanks guys. You all are top notch.

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  • jh

    They are promoting muftas as opposed to saturated fats. I.e. olive oil but not fatty beef, or bacon, pork fat..

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  • Elizabeth

    What if I’m 5 months off my aggressive breast cancer treatments and now I feel this pain on my left side. Lower left side. Am I at a greater risk to die. I forgot to mention that I’ve been cleaning my room and noticed while reading all this that I do feel a tiny bit nautious?

  • Mary

    I have to agree. Eating a very high calorie diet means the HEART (lets not forget our old pal) has to beat many times more, every minute all those calories are being digested.. I think we would all do well, to measure our food in what we can hold in the palm of our hand. The human body has proven that excess food and harmful dietary practices, along with chemical laced soda, is the root cause of almost all health problems today ! The PALM of your hand. Portions HAVE to become smaller, if WE are to become healthier (and smaller).

  • Stephanie Stuart

    Interesting Mary, do you have any favorite resources that elaborate on the palm measurement? I’ve heard of that before, but I’d like to read more. Thanks

  • Chrissy

    Please update your article to include non-alcoholic fatty liver disease. It is so common now and most people don’t even know it exists.

  • Global Healing Center

    You bring up a good point, it’s a huge problem. I’m actually working on a few other separate articles that discuss it, stay tuned.

  • Global Healing Center

    Correct, trans and saturated.

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  • Mike Cummo

    Can a fiber supplement like Metamucil help aid the liver in easing it’s ‘workload’ so to speak?!

  • Global Healing Center

    Well, sort of. Fiber helps digestion and if you’re not getting enough, you could potentially say that adding a fiber supplement would fill that void. In that context, maybe. I wouldn’t make a blanket statement by any means though that Metamucil helps your liver.

  • Stephen

    What if you are taking a statin drug for cholesterol control ? Will it conflict with Livatrex ? I have been using Pravastatin for 3 years, Lipitor for 5 years before that. Some statins do negatively affect the liver, but a recent long-range study I read a summary of indicates Pravastatin is much less harmful.

  • emh

    i was recently diagnosed with fatty liver… i’m a little skeptical about your liver cleanse kit? i had my gallbladder out about 5 years ago… most of these questions are about 2 years old… anything more recent?

  • Global Healing Center

    What are you wondering?

  • Global Healing Center

    We haven’t heard of any issues but that doesn’t mean it’s impossible. You might want to check the included literature with those drugs and see if any of them mention warnings regarding the herbs and ingredients in Livatrex.

  • dbns

    I’ve read that excessive use of Agave Nectar causes non-alcoholic fatty liver disease, after using it freely for 13 years before this information came out! I’m now always getting dull cramp pains on my right side fifteen minutes after eating too much protein (usually nuts) or if my system is backed up with too much food it can occur about an hour or so after eating and the pain lasts just about 2 hours. I’ve been having this since I began consuming Agave Nectar and though I ditched it four years ago, I’m damaged by it and have to watch my protein intake! I hope you will include Agave Nectar in your article to warn others about it, thanks!

  • dbns

    …sorry, this reply was supposed to be for Global Healing Center, I hit the wrong reply button! 😉

  • KellynJason Baines

    I have numerous calcus stones in my liver and hepatic duct but I also have colitis so raw fruit etc is a no go for me I like tuna but while I have the stent in to reduce the inflammation in my liver my doc recommended a low protein diet can I still eat tuna it’s about all I can eat without pain that and Rice Krispies thanks in advance

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