The Health Benefits of Serrapeptase

by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM Published on , Last Updated on

Discovered in the early 1970’s, this proteolytic enzyme was isolated from the Serratia species of bacteria located in the intestines of silkworms. Serrapeptase, also called serratiopeptidase, is truly a superior enzyme that provides strong, healthful properties. Today Serrapeptase is used all over Europe and Asia in clinical settings. It has the ability to break down non-living tissue in the body.

Serrapeptase is perhaps one of the world’s most exciting enzymes being studied in regard to its wide variety of clinical applications. Currently, especially in Europe and Asia, it is clinically used for many, many negative health conditions. One of the most well-known proponents for this enzyme was the German physician, Dr. Hans Nieper. He had great success supplementing with serrapeptase to promote normal heart and circulatory system health.

How Does Serrapeptase Work?

Serrapeptase is an immunologically active enzyme. It can bind itself to the alpha 2 macroglobulin in our plasma where it is shielded from the immune system while retaining its enzymatic activity, and in this way, it is transferred to the sites where it is needed in the body. It is this same type of powerful yet specific action that allows silkworms to eat its own protective cocoon, digest it without any side effects and fly away. Amazingly, serrapeptase has the distinct ability to digest only non-living tissue allowing the old toxic layers that clog the digestive system and the lining of our arteries to dissolve. This is one reason why it’s so good at keeping arterial deposits from building up after heart surgery.

Health Benefits of Serrapeptase

1. Atherosclerosis

Dr. Nieper found that Serrapeptase could dissolve blood clots and reduce varicose veins. Other studies from Germany have found that serrapeptase could effectively remove atherosclerotic plaque without hurting any of the healthy cells along the arterial wall.

2. Chronic Redness

Multiple studies confirm it’s resistance to Redness and it has been used for this reason in the reduction of chronic or acute conditions.

3. Helps with Traumatic Injuries

Serrapeptase is widely used in Europe as a supplement for traumatic injury (such as sprains and torn ligaments), as well as the swelling associated with post-surgical patients.

4. Pain, Edema and Swelling

Serrapeptase has been approved as a standard remedy in many European countries for swelling. A double-blind German study on the enzyme found that it could reduce swelling by up to 50% in post-operative patients. Patients taking serrapeptase experienced statistically significant less pain than the control groups and, by the 10th day of the study, all patients taking the serrapeptase were completely pain-free.

5. Helps with Cystic Breast Disease

In a double-blind study, Serrapeptase was found to reduce breast pain, breast swelling and induration in 85.7% of the patients taking the supplement. This is related to the fact that the enzyme possesses fibrinolytic, proteolytic and anti-edemic properties.

6. Helps Infections in the Ear, Nose, and Throat

In one double-blind study, patients with acute or chronic ear, nose or throat diseases found significant symptom regression with Serrapeptase. The enzyme is able to reduce the viscosity of mucous, thus facilitating drainage.

7. Helps with Carpal Tunnel Syndrome

Recent studies confirm the use of this enzyme for the reduction of symptoms associated with carpal tunnel syndrome.

8. Other Potential Benefits

Serrapeptase is currently being studied and used for a vast array of applications for human health and disease prevention. This includes therapeutic use for nerve damage, Multiple Sclerosis, chronic ear infections, hay fever, lung congestion, swollen glands, laryngitis, rhinitis, chronic pain, arthritis, back and neck pain, diabetes, ulcers, osteoporosis, prostate problems, rheumatoid arthritis, sports injuries (both prevention and recovery), post-operative scars and lesions, varicose veins, arterial diseases, angina, blood clots, anti-aging, restoration of healthy fibrin metabolism and reduction in C-Reactive Protein.

How to Read the Units of Measurement for Serrapeptase

Serrapeptase is measured in SUs (Serrapeptase Units). This comes from the Japanese and Korean Pharmacopeias, whereby one unit of Serrapeptase is the activity yielding a product equivalent of 1.0 μg of Tyrosine per minute at pH 9.0 and 37 degrees Celcius on a casein substrate.

Where Can I Find The Best Source of Serrapeptase?

VeganZyme® contains a 100% vegan form of Serrapeptase cultured from Serratia marcescens. It comes from all vegetarian, non-GMO sources, is kosher certified, gluten free, contains no animal product and is completely suitable for vegetarians and vegans. VeganZyme is the most advanced full-spectrum systemic and digestive enzyme formula in the world and is free from fillers and toxic compounds. This formula contains digestive enzymes which help digest fats (lipids), sugars, proteins, carbohydrates, gluten, fruits and vegetables, cereals, legumes, bran, nuts and seeds, soy, dairy and all other food sources. VeganZyme may also be used as a systemic enzyme blend to break down excess mucus, fibrin, various toxins, allergens, as well as excess clotting factors throughout your body.


  1. Kee WH, Tan SL, Lee V, Salmon YM. The treatment of breast engorgement with Serrapeptase (Danzen): a randomised double-blind controlled trial. Singapore Med J. 1989 Feb;30(1):48-54.
  2. Mazzone A, Catalani M, Costanzo M, Drusian A, Mandoli A, Russo S, Guarini E, Vesperini G. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990 Sep-Oct;18(5):379-88.
  3. Kakinuma A, Moriya N, Kawahara K, Sugino H. Repression of fibrinolysis in scalded rats by administration of Serratia protease. Biochem Pharmacol. 1982 Sep 15;31(18):2861-6.
  4. Esch PM, Gerngross H, Fabian A. [Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase– a prospective study]. Fortschr Med. 1989 Feb 10;107(4):67-8, 71-2. German.

†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. Global Healing Center does not dispense medical advice, prescribe, or diagnose illness. The views and nutritional advice expressed by Global Healing Center are not intended to be a substitute for conventional medical service. If you have a severe medical condition or health concern, see your physician.

  • Krakondack

    It sounds promising, but it seems like it would have to be injected to have any effect. How would it otherwise survive the digestive enzymes, and pass into circulation? Until that’s clear, I don’t see how I can buy into this.

  • joe

    If that is the case, than how to justify the use of antibiotics , will the digestive enzymes not have the same effect that u had mentioned.

  • matt

    There are truly many benefits to serrapeptase, find them out at –

  • anneabell

    sounds to good to be true I just read that the product was recently recalled as they had no control studies i would love more informaiton on this

  • Vanessa

    I wanted to know If this would work on ednometriosis?

  • jen

    My sister has been trying
    to get me to take this for years. I finally agreed with her because I need to take Advil everyday for muscle stain from my job . I’ve been taking it for a week and have improvement in my pain. I haven’t taken any Advil since started it.

  • Cassie

    Vanessa, do you have endo? And if so, have you tried enzymes? I have an endometrioma cyst on my ovary and likely have endo. I just recently started proteolytic enzymes mainly to break down the cyst, but I just wanted to see if you were having any luck?


  • Happi

    It is an enzyme as are all the digestive secretions, if other prescribed pharmaceuticals can survive the digestive process I am sure that you will find that this product (as it is natural) will surely do the same thing quite with much less damage to the body as it is bioidentical

  • deepti

    Is it helpful in treating eye floaters?

  • Global Healing Center

    I’ve seen some discussion on other forums about serrapeptase and eye floaters. I wouldn’t say it treats it but the limited information I saw sounded positive. Please let us know what you discover if you research it more!

  • Love

    Because it’s enteric coated google why pills come in that form

  • Loc

    The pills are enteric coated which protects it from the gastric juices it not being absorbed in the stomach but the small intestine which it’s absorbed from the blood stream

  • ahk

    Has any research been done on serrapeptase and autoimmune disease like celiac?

  • Global Healing Center

    Haven’t seen anything, any other readers?

  • AIDS

    It gives you AIDS, be warned.

  • josh

    Has any research been done on serrapeptase and pulmonary fibrosis? Fast responses will be appreciated, thank you.

  • Global Healing Center

    Do you have a paper due or something? My quick search on Pubmed didn’t yield anything but that may not cover all research that exists.

  • Narinder Singh

    Are their any harmful effects of daily use of serapeptidase .

  • Global Healing Center

    Shouldn’t be, many people take it every day.

  • Pingback: The Health Benefits Of Serrapeptase | Healthy Sauce()

  • Cathi Oakes Tinney

    Hey pls tell me this will help yr round sinus mucus and chronic drainage. Pls.

  • Global Healing Center

    We have heard people say it’s helped thin up their mucus. Hard to say absolutely until you try it.

  • Cathi Oakes Tinney

    great. any suggestions for year round chronic allergies? nothing helps.

  • Global Healing Center

    Have you tried natural antihistamines?

  • Cathi Oakes Tinney

    no i havent. thanks and i will. i was not aware of these. will let you know how goes.

  • Reccia May Villanueva

    do you have distributor/store here in the Philippines?

  • maestra545

    Enteric capsules of serrapeptase are available from Source Naturals. I spoke to a customer representative and they assured me that they are forumlated for just that purpose.

  • Saiful Rimkeit

    I suppose this enzyme takes away clots because clots are composed of dead tissue, dead blood cells and other allied matter without affecting the rest of the blood structure and the enzyme becoming a blood thinner?
    If Dr Edward Group III DC, NP, DACBN, DCBCN, DABFM
    or someone qualified has the time, could this also be answered?

    Thank you.

    Geez, some of these posts are fairly old. Doc, you need a more effective way to expose these wondrous products and explanations to the World.

    Signed, oOne who seeks answers from NDs, osteopaths, herbalist MDs, DCs, etc.

  • Krista Burkling

    I am very interested in trying this. I am curious though. Is this safe for children & breastfeeding mothers? My 4 year old could really benefit from this & so could my husband & I. I am breastfeeding our 8 month old though.

  • Global Healing Center

    You can always check with your doctor but nobody should have any trouble with enzymes. They’re just like little health power ups.

  • Pingback: Natural remedies for Endometriosis? |()

  • Colleen

    Currently I take tumeric 750mg am/pm for various aches and pains. It has helped, but wondering how the 2 might interact or if one is better on its own than the other? I have some arthritis, plantar fasciitis and treated surgically for uterine cancer.

  • Jenna Ice

    Its helped me with this ! like emmediate relief. also take capryllic acid with it

  • Jenna Ice

    it helps!

  • raelynnd

    does this help with blocked fallopian tubes?

  • patti walsh

    Hi, My doctor advised me to take Natural D-Hist by Ortho Molecular for allergies and it helped me with no side effects or drowsiness. Hope it helps!

  • Stephanie J Little Wolf

    Enteric coated works well on an empty stomach. This stuff is really powerfull. It causes herxing so use slowly at firzt and do lots ot detoxing. 10 days of being very tired……. but well worth it

  • Paul James Vecchio

    I’am 68 yrs old.I got A Fib from using a Device on my Feet ,like Thongs that you Plug into a Tens Unit. (New Device) (What follows is my opinion and backed up by real Facts) This Device sends a Electrical Surge up your legs every 10 seconds or so to Treat Nueropathy from Diabetes) (you can set the Rate ) Anyway,I used the Device for 4 months and Noticed How Tired I was. So I ended up in the Hospital with Angina,and at that time I was told that I had A Fib.I stopped using the Device 2 weeks earlier.So,I tried to tell the Doctors, (students at U.N.M.C. Omaha Ne.) University Hopital,that I got A Fib from this Device, (becuse I thought it Changed my Electrical System in My Heart) of couse they Laughed at me!So,I was put on Xeralto.2 months later,I Noticed my Hands and Fingers Falling asleep and being Numb.I also had Hemroids bad,( which I never had before),and Blood in my Stools.So I stopped taking Xeralto,and started Researching Alternative Meds.Thats how I Found Serrapeptase. After Taking 250000.00 (two hundred fifty thousand SU ‘s) on an Empty Stomach for 41/2 months, I called and said my A Fib was Gone!They Immediatley had me come in the Heart Center and said to me that I could not Stop taking Xeralto! She was a P.A. at the Heart Center of U.N.M.C. because my Heart Dr. was out of town at the time.She actually yelled at me ! I insisted that I was Taking Serrapeptase ,and she got mad and said,You can’t do that,I’ll put you on Cumidin or Warafin,and my Reply was,that those were Rat Poison,she then said,well,we will monitor you.I said,what am I a Lab Rat ? You’ll get a clot and Stroke out!I said I will Continue to Take Serrapeptase,Her Reply was,You Can Not Do That! Watch Me ,I said.So She arranged a Collar Heart Monitor that I wore for 5 Days. After 5 Days,I returned the Heart Monitor and they Removed it,and was told to call in 2 weeks later.I called in and they had no results at that Time. A week later I got a Call from the Heart Center,and was told that my Heart was in normal Sinic Rytham.I Know that They are Astonished ! No Further Contact from them! My A Fib is Gone! I still Take Serrapeptase Today!All this can be Verified! Paul James Vecchio Feb,2016.

  • Brian

    Are there any randomized placebo controlled studies available? In Japan, these stuff been pulled from market due to ineffectiveness according to Wikipedia. Anyone have an answer for that?

  • Pingback: Serrapeptase: The Miracle Enzyme That No One Seems To Know About | Collective-Evolution()

  • Pingback: Serrapeptase: The Miracle Enzyme That No One Seems To Know About | Best Natural News()

  • Pingback: A Magic Enzyme? – Real News Now()

  • Pingback: A Magic Enzyme? | Michigan Standard()

  • Pingback: A Magic Enzyme? | We Seek the Truth!()

  • Pingback: A Magic Enzyme? | We Seek the Truth!()

  • Pingback: The Healing Properties of Serrapeptase – Real News Now()

  • Pingback: The Healing Properties of Serrapeptase | Michigan Standard()

  • Pingback: The Healing Properties of Serrapeptase | We Seek the Truth!()

  • Pingback: The Healing Properties of Serrapeptase | We Seek the Truth!()

  • jdbaird

    It really does work, I’ve personally heard from people who had massive scarring from surgeries that serrapeptase caused the internal scarring to just go away. Also a friend of mine who had warts all over his hands and arms, took serrapeptase and the warts just flaked and fell off.

  • Jimmy Yost

    The serrapeptase I’m taking now has 120,000 serrapeptadase units per capsule. The instructions on the bottle say to take only one per day. I can tell it’s working but it’s going slow (for middle ear congestion). Can I take two capsules per day?

  • سعد يوسف البلداوي

    Some suppliers sell it with enteric coating. which will pass the stomach and dissolve after that. this makes it more effective.

  • سعد يوسف البلداوي

    Any tests of interaction with other supplements ? pills like Bee Pollen, royal jelly, Propolis, vitamin E & C, & Curcumen..would that require seperate timing or must drop some of these ?

  • Pingback: Arthritis – The Rust in Your Joints! | Soulfully Connecting()

  • barbbat

    I do (take two of the same dosage as you) and I’ve had no problems.

  • barbbat

    Not experienced any, but remember to take it with lots and lots of water so the capsule reaches your small intestine instead of being destroyed by stomach acid. I always try to stand up for about ten minutes (walk, clean, etc) until I feel the cap is out of my stomach. I take two 120,000 units per day on an empty stomach and have had no problems. My sinuses and ears have cleared up, but I’m really hoping for clean arteries!!

  • Pingback: The Health Benefits of Serrapeptase | The Health Coach()

Top Selling Supplements

Colon Cleanser Oxy-Powder® is the top quality colon cleanser. Promotes optimal colon health and regular bowel activity. Learn More

Liver Cleanse Kit This complete liver cleansing kit is a comprehensive approach to cleansing your liver. Learn More

Get to know Dr. Group

  Our Company