Anise, a plant native to Greece and Egypt, has been used since the seventh century to address health ailments and may best be identifiable today for its licorice flavor. During biblical times, taxes could be paid in crops, anise was one of them. The Romans cultivated anise and greatly exploited (in a good way) its many health benefits. Today, many people use anise to support digestion, which is not much surprise since it is related to caraway, dill, and fennel- also often fingered as digestive support agents.
However, one advantage that anise has over its similar counterparts is that it’s much more powerful against, and resistant to, harmful organisms. In lab and clinical trials, anise stands its ground when faced up against harmful organisms and it’s even more potent when combined with other, similarly beneficial herbs. For example, when anise seed is combined with horopito pepper, it’s efficacy against candida yeast infections may be up to 32x more effective.
Anise Seed and Annoying Insects
Mosquitoes are known to carry diseases and present a very serious public health issue to many communities all over the world. Because of a laundry list of negative health effects associated with chemical pesticides, there is much focus and effort on developing effective pest control measures using natural compounds. Research has shown that anise seed oil is toxic to mosquito larvae and offers potential as an essential oil that may be effective at controlling vector-borne disease carrying agents. 
The Plant Protection Department at Turkey’s Akdeniz University evaluated essential oils of several therapeutic herbs, including anise, eucalyptus, mint, and basil for efficacy against mosquitos. All the samples were deemed effective, although to different degrees, and anise was identified as the most effective. 
Mosquitos aren’t the only flying pests anise seed has defeated. Sterling International, a company based in Washington, evaluated common essential oils against several species of wasps. Anise seed was one of several observed as effective and having potential as a natural, eco-friendly wasp control measure. 
Anise Seed vs. Harmful Organisms, Candida, Yeast, and Fungus
With anise seed’s demonstrated efficacy against insects, it’s no surprise that the amount of research supporting the toxicity of anise seed to other harmful organisms is staggering and comes from all corners of the globe.
Research conducted at The University of Mississippi’s School of Pharmacy evaluated various plant extracts for their resistance to fungus and noted that anise seed was the best at inhibiting both fungal and microbial activity. 
Croatia’s University of Zagreb conducted similar research and had similar conclusions. When anise extract was put to the test against seven strains of yeast and four strains of fungus, in vitro experiments showed anise to retard both fungus and yeast proliferation. 
Additionally, Iraq’s University of Mosul also tested essential oils for activity against several harmful strains of bacteria, including staph, e. coli, and salmonella. Essential oil of anise seed demonstrated the highest resistance to bacteria. 
Supplementing With Anise Seed
Perhaps the best argument for anise seed came from the Immunology Research Institute and Clinic in Nagoya Japan. For patients undergoing antibiotic or immune-system-suppressing therapies, chronic urinary infection of candida can be a constant problem. In 2010, the Institute conducted a study that involved 39 such patients and concluded that a natural, plant-based compound with demonstrated resistance to fungus could offer an effective approach. 
If fungus, candida, or yeast is a problem in your life, I recommend cleansing your body and following a body cleansing diet. For additional support, Mycozil is product that contains anise seed and active horopito in the most effective ratios, making it an ultra powerful weapon against nail and toenail fungus, candida, yeast, and other fungal infections.
- Dr. Edward F. Group III, DC, ND, DACBN, DCBCN, DABFM
- Kimbaris AC, Koliopoulos G, Michaelakis A, Konstantopoulou MA. Bioactivity of Dianthus caryophyllus, Lepidium sativum, Pimpinella anisum, and Illicium verum essential oils and their major components against the West Nile vector Culex pipiens. Parasitol Res. 2012 Dec;111(6):2403-10. doi: 10.1007/s00436-012-3097-1. Epub 2012 Sep 6.
- Erler F, Ulug I, Yalcinkaya B. Repellent activity of five essential oils against Culex pipiens. Fitoterapia. 2006 Dec;77(7-8):491-4. Epub 2006 Jul 7.
- Zhang QH, Schneidmiller RG, Hoover DR. Essential oils and their compositions as spatial repellents for pestiferous social wasps. Pest Manag Sci. 2013 Apr;69(4):542-52. doi: 10.1002/ps.3411. Epub 2012 Oct 19.
- Tabanca N, Bedir E, Ferreira D, Slade D, Wedge DE, Jacob MR, Khan SI, Kirimer N, Baser KH, Khan IA. Bioactive constituents from Turkish Pimpinella species. Chem Biodivers. 2005 Feb;2(2):221-32. Erratum in: Chem Biodivers. 2006 Jul;3(7):825.
- Kosalec I, Pepeljnjak S, Kustrak D. Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae). Acta Pharm. 2005 Dec;55(4):377-85.
- Al-Bayati FA. Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts. J Ethnopharmacol. 2008 Mar 28;116(3):403-6. doi: 10.1016/j.jep.2007.12.003. Epub 2007 Dec 14.
- Marotta F, Naito Y, Bishier MP, Jain S, Yadav H, Minelli E, Kumari A, Solimene U, Sollano J. Subclinical candiduria in patients with gastrointestinal malignancies: a preliminary study on the protective effect of a natural phytocompound. J Biol Regul Homeost Agents. 2010 Jul-Sep;24(3):317-24.