It is possible that you suffer from a B-12 deficiency, either related to the medication or to some other factor. Many people find that B-12 absorption decreases over time due to food choices, poor digestion, decreased production of intrinsic factor, food processing, or for other poorly understood reasons. Probably the best way to test whether you are deficient is to get a B-12 shot or, even easier, to try a sublingual methylcobalamin supplement, a very good form of B-12. This form is absorbed under the tongue and bypasses the digestive tract. A good product is called Unique B-12.
Please keep in mind that PPIs decrease hydrochloric acid secretion and may leave you more susceptible to bacterial, viral, fungal, and parasitic infection. I would strongly suggest working with a naturopath to investigate some natural options to the medications. Betaine HCL, digestive enzymes, and cleansing may provide some options to help restore your body to health rather than simply decreasing a natural function of your body, i.e. suppressing acid production. An excellent cleanse protocol is located at
www.ghchealth.com/liver-and-gallbladder-flush.html. The liver/gallbladder portion of this cleanse can be repeated several, usually 3 or more, times at 5-10 day intervals to help detoxify the liver, a key order for digestion as well as detoxification.