Zeotrex FAQ's

Below is a list of the top five most frequently asked questions concerning Zeotrex®.

  1. Does Zeotrex® cross the Blood Brain Barrier? Answer
  2. Why won't the Zeolites absorb the trace minerals and herbs in Zeotrex®? Answer
  3. Does Liquid Zeolites in Humic acid contain active bacteria and "aflatoxin" producing fungus which are toxic to the body? Answer
  4. Do you think that the manufacturing process may cause a breakdown in the alumina-silicate bond, allowing free floating aluminum to be absorbed by the body? Answer
  5. In non fibrous Clinoptilolite based zeolites, the alumina-silicates are inert in the human body correct? Answer

1) Does Zeotrex® or other Zeolites Supplements cross the Blood Brain Barrier?

I must start by addressing the 'unsubstantiated' claims made by producers and sellers of other zeolites products out there concerning their assertions that humic/fulvic acid in their products is somehow involved in their zeolites being able to cross the blood-brain barrier.

Definition of Blood Brain Barrier

Let's define the Blood Brain Barrier before moving forward:

The standard definition found in Physiology & Anatomy texts is: Blood-brain barrier, A mechanism that controls the passage of substances from the blood into the cerebrospinal fluid and thus into the brain and spinal cord.

The blood-brain barrier lets essential metabolites, such as oxygen and glucose, pass from the blood to the brain and central nervous system (CNS) but blocks most molecules that are more massive than about 500 Daltons. This is a low mass in bio-molecular terms and means that everything from hormones and neurotransmitters to most viruses and bacteria are refused access to the brain by the blood-brain barrier.

Key Functions of the Blood-Brain Barrier

Blood Brain Barrier

The key functions of the Blood-brain barrier are: Protecting the brain from "foreign substances" (such as viruses and bacteria) in the blood that could injure the brain, shielding the brain from hormones and neurotransmitters in the rest of the body, and maintaining a constant environment (homeostasis) for the brain.

Some companies are claiming that because their zeolites-based products are made with and/or contain humic/fulvic acid that this makes their product capable of crossing the blood brain barrier.

In doing a thorough examination of the scientific and research literature, I can find no reference to actual bona fide in-vivo (in the body) tests substantiating these claims. I am aware of in-vitro (test-tube) studies wherein many ionic colloidal minerals products have been found to be able to cross an in-vitro artificial-membrane barrier, even more so when certain acid or alkaline (especially alkaline) components are added to the equation, but these are for in-vitro studies specifically.

I can only assume that if these companies are referring to "scientific studies" on the subject they are referring to these in-vitro based studies and taking those results and assuming that those same results would apply to an in-vivo (natural/biological) outcome, which is simply not going to be the case. Or at least has not been proven yet. Too many mitigating in-vivo biological factors of a highly complex nature will not apply to what a simplistic in-vitro study might result in, especially where the highly complex nature of the blood-brain barrier is concerned.

Though the mB!™ trace mineral complex in Zeotrex® contains humic and fulvic acid components (that is a totally separate ingredient from the Zeotrex® zeolites ingredient), the zeolites used in Zeotrex® are not made using humic or fulvic acid, yet the Pureodine™ processed zeolites in Zeotrex® possess amazing sought-for qualities that match and even exceed many aspects of competitor zeolites. As I have tested and observed, the clinical-based use and feedback of Zeotrex done before taking this product to market showed incredible results and benefits that met my criteria for this formula. This brings me to the next point.

If indeed zeolites products should be found, via actual scientific-based in-vitro studies, to actually pass the blood-brain barrier as other companies are currently claiming, it would in all likelihood not be because of the humic/fulvic acids. If any formula crossed the blood-brain barrier, it would be Zeotrex® because the Pureodine™ processed zeolites possess the same or better observed biological effects considered to be unique to zeolites. This is a very important point given that the processed zeolites used in Zeotrex® are not made using humic/fulvic acids, although Zeotrex® does contain naturally occurring humic and fulvic acids!

With that being said, we have had people tested for heavy metals via hair, urine and saliva analysis and seen a dramatic reduction and even complete removal from the body after just 30-90 days of using Zeotrex®. We are currently the only company in the world that has combined zeolites with an organic herbal chelating base specifically designed to cleanse the body of heavy metals and toxic chemicals.

There most likely is a big misconception about heavy metals being stored in the brain. Most heavy metals in their free state do not readily cross the blood-brain barrier. They are too large or must be broken down and bonded to a carrier molecule. However, mercury and aluminum are very common metals that are often linked to brain dysfunction mainly due to the presence of organic forms in the environment. Please see the research below on Mercury and Aluminum and their ability to cross the blood-brain barrier.

Supporting Research

1) Mercury Neurotoxicity: Mechanisms of Blood-Brain Barrier Transport

Aschner M, Aschner JL. — Department of Pharmacology and Toxicology, Albany Medical College, NY 12208.

"Mercury exists in a wide variety of physical and chemical states, each of which has unique characteristics of target organ toxicity. The classic symptoms associated with exposure to elemental mercury vapor (Hg0) and methylmercury (CH3Hg+; MeHg) involve the central nervous system (CNS), while the kidney is the target organ for the mono- and divalent salts of mercury (Hg+ and Hg++, respectively). Physical properties and redox potentials determine the qualitative and quantitative differences in toxicity among inorganic mercury compounds, while the ability of MeHg to cross the blood-brain barrier accounts for its accumulation in the CNS and a clinical picture that is dominated by neurological disturbances. This review gives an up-to-date account of mercury's physical and chemical properties and its interaction with biologically active sites pertinent to transport across the blood-brain barrier, a major regulator of the CNS millieu."

Learn More About This Study - PMID: 2190116

2) Brain Uptake, Retention, and Efflux of Aluminum & Manganese

Yokel RA. — College of Pharmacy and Graduate Center for Toxicology, University of Kentucky Medical Center, Pharmacy Building, Rose Street, Lexington, KY 40536-0082, USA.

"My colleagues and I investigated the sites and mechanisms of aluminum (Al) and manganese (Mn) distribution through the blood-brain barrier (BBB). Microdialysis was used to sample non-protein-bound Al in the extracellular fluid (ECF) of blood (plasma) and brain. Brain ECF Al appearance after intravenous Al citrate injection was too rapid to attribute to diffusion or to transferrin-receptor-mediated endocytosis, suggesting another carrier-mediated process. The brain:blood ECF Al concentration ratio was 0.15 at constant blood and brain ECF Al concentrations, suggesting carrier-mediated brain Al efflux. Pharmacological manipulations suggested the efflux carrier might be a monocarboxylate transporter (MCT). However, the lack of Al (14)C-citrate uptake into rat erythrocytes suggested it is not a good substrate for isoform MCT1 or for the band 3 anion exchanger. Al (14)C-citrate uptake into murine-derived brain endothelial cells appeared to be carrier mediated, Na independent, pH independent, and energy dependent. Uptake was inhibited by substrate/inhibitors of the MCT and organic anion transporter families. Determination of (26)Al in rat brain at various times after intravenous (26)Al suggested a prolonged brain (26)Al half-life. It appears that Al transferrin and Al citrate cross the BBB by different mechanisms, that much of the Al entering brain ECF is rapidly effluxed, probably as Al citrate, but that some Al is retained for quite some time. Brain influx of the Mn(2+) ion and Mn citrate, determined with the in situ brain perfusion technique, was greater than that attributable to diffusion, suggesting carrier-mediated uptake. Mn citrate uptake was approximately 3-fold greater than the Mn(2+) ion, suggesting it is a primary Mn species entering the brain. After Mn(2+) ion, Mn citrate, or Mn transferrin injection into the brain, brain Mn efflux was not more rapid than that predicted from diffusion. The BBB permeation of Al and Mn is mediated by carriers that may help regulate their brain concentrations."

Learn More About This Study - PMCID: PMC1241228

If any company has documented research via in-vitro studies that I might have missed please let me know.

What This All Means For Zeotrex®

The answer to the inquiry would be that there is currently no scientific proof that Zeotrex® or any other Zeolites formula with or without the components humic and fulvic acid will cross the Blood Brain Barrier.

Once absorbed into the blood stream (as mineral and protein bound macro compounds) they would simply flow through the blood to the liver where these macro compounds are then broken down into their simple constituent parts and reconfigured back into metabolites (proteins, fats, sugars, mineral carriers, etc.), substrates (to be utilized in enzyme driven activities), and special individuated macro compounds (such as polysaccharides, antioxidants, etc.), of which only those metabolites/compounds that pass the blood-brain barrier must be able to bind to oxygen, sugar, sodium or potassium carriers to cross the blood-brain barrier. Interestingly, the oxygen, sodium, glucose and potassium binding compounds that do cross the blood-brain barrier (not all do, because of other mitigating factors too complex to elucidate here) are also the ones that are safe for crossing the blood-brain barrier.

So, according to the science of Physiology and Anatomy, Zeotrex® in its non-physiologically/bio-chemically converted forms may not pass the blood-brain barrier, only those compounds that have been properly reconfigured in the liver and bound to the appropriate carrier would be permitted to pass the blood-brain barrier. However, this does not exclude the fact that once broken down by the liver or bound to a carrier that the components in Zeotrex® would not cross the blood-brain barrier. It is just that this has not yet been scientifically proven.

What happens to all those other components that don't (and are not supposed to) pass the blood-brain barrier?

They go to other organ systems and tissues of the body where they are allowed to pass the appropriate organ system's blood barriers. The body is full of blood-organ barriers, each a part of the body's immune system, intended to only allow certain things to pass and not allow others. When these blood barriers are challenged or actually break down such things as bacteria and viruses break through to cause havoc and mayhem, often to a very dangerous level.

One good example of a blood-organ barrier breakdown incursion is that caused by H5N1 (avian bird flu), that stimulates the respiratory (lung) immune response that creates a Cytokine storm, with a total break down of the blood-respiratory barrier and results in the dissolving of respiratory tissue into mush. That of course is an extreme example. But it does illustrate how important it is to keep the body's immune system healthy, including making sure that the tissues of the body are rich in certain essential minerals, since the tissue mineral levels (each intrinsic to a specific mineral or mineral group) may be one of the key determining factors in how effective a blood-organ barrier system works. That's my take on the subject.


2) Why won't the Zeolites absorb the trace minerals and herbs in Zeotrex®?

The repelling action of the negative charges carried by the individual components of the formula is the key to its stability and the reason that the individual ingredients are not absorbed into the zeolites matrix. Imagine a large container filled with magnets that have only a negative pole; no matter how much you shake it or how long you leave it, the magnets will always maintain a minimum distance between themselves simply because the negative poles constantly repel each other. It is basically the same with the ingredients in Zeotrex® as they repel each other and keep their distance.

This attraction/repulsion idea is also essential to understand how Zeotrex® removes chemicals and heavy metal toxins: 1) the negatively charged mineral-based compounds displace (dislodge) positively charged heavy mineral-based compounds from tissues and fluid systems and 2) those positively charged heavy metal-based compounds are in a free state when they are taken up by the negatively charged zeolites matrix. This, in turn neutralizes the chemical and heavy metals charge, allowing the toxin-laden zeolites matrix to be eliminated from the body. The zeolites bind to the toxins and form a compound that is inert or inactive and ready to be eliminated through the body's normal detoxification pathways.


3) I have heard that Liquid Zeolites in Humic acid contain active bacteria and "aflatoxin" producing fungus which are toxic to the body. Can you explain this?

I have been working hard over the last two years with one of the worlds top zeolites specialists to make our own organic chemical and heavy metal detox formula called Zeotrex® containing herbs as well as zeolites. It took along time to figure out a way of producing a safe form of zeolites without using a Bromine or other toxic bath.

To a large degree the Humic Acid question is a sort of Apples-vs-Oranges thing. Let me explain.

I'm aware of the concern about humic acid–based solutes possessing the potential to contaminate a zeolites product. We are of course talking about the products that contain over 50% of actual processed zeolites ingredient to which a humic acid-based solution has been added. The detox-zeolite formula we are introducing is not a 'pure' zeolites-based product, but one that is a complex cleansing product that 'contains' zeolites and angstrom –colloid organic herbs.

Our Zeotrex® formula does contain humic acid, which may raise concerns for those who take the simplistic view that ALL humic acid ingredients possess bacteria, which is patently not true. First, the humic acid we use is not a 'pure' humic acid that's been added to the product, like the culprit other zeolites products may have done, but instead the humic acid (also known as humate) is an integral part of the mB! liquid trace mineral base added to our product as an ingredient.

mB! is made utilizing our Citritol micro-fractionating process that takes a liquid-based fulvate-rich liquid trace mineral complex mixture extracted from mesozoic era deposits that are rich in humates, which turn to humic acids when subjected to moisture, that in turn activates fulvate activity. Yes! Bacteria are actually a part of this humic/fulvate activation process, as some believe that these are the bacteria's so essential to the soil and hence all plant life.

The problem is, these bacteria were not intended to jump the food chain and end up in a consumable end-product. Their part in the food chain ends at the root level of the plant where their contents (minerals, enzymes, proteins, etc.) are consumed by a plants roots and the castes (the shell of soil bacteria) are impacted against the root wall (often seen as the loose brown crusty stuff (not quite turned into 'soil') that can be scraped off with a finger nail) or is discarded to become composted into and further nutrify the soil itself.

First, the liquid trace mineral complex ingredient we put through the Citritol process to make mB! has been processed and filtered and utilizes an extensive customized filtration system specially made for filtering out things over a certain angstrom size, of which bacteria are included, while allowing the smaller mineral colloids to pass through, so it has no bacteria present. Also, the pH of the raw mineral ingredient we receive is around 3.5, so acidic that few if any bacteria would be able to survive in that low of a pH environment.

This raw mineral ingredient also possesses a strong negative ionic charge, which is not conducive to bacteria life. All these qualities are passed through to our Citritol processed mB!, and in fact further strengthened, since the processing technology intrinsically is incompatible to any bacteria, and the pH is further driven down making this solution totally incompatible to bacteria... And yet it still contains fulvic/humic acids, only now in a highly stabilized solution.

Those qualities are likewise passed onto any product to which the mB! is then added, provided the mix to which mB! is added is of a stabile nature that won't precipitate a bacteria 'incidence,' which this product is designed to be and meet (it's actually part of our cGMP/HACCP compliant and Kosher certified standards).

Now to the unique zeolites formula we develop. First, the raw material provided for processing into our zeolites finished product is from a pure clinoptilolite clay deposit free of fulvates and humates. My own inspection of the material we received appears to validate this as when the clay is put through the process there is no 'alum' taste (and indicator of fulvic acid presence) and the solution does not possess any kind of yellowing of the liquid, either at point of finishing the process or after the solution has stood for some time (yellowing or tinting thereof would be an indicator of humic acid being present).

Further, the protocols used in making our zeolites possesses an intrinsic nature that is not compatible to bacteria and the end 'glycerite-based' product is extremely bacteriostatic, so high in fact that this bacteriostatic quality is considered to posses 'absolute preservation' qualities in the concentrate state. Therefore, our zeolites colloid complex is not a culture medium that allows for bacteria to survive and/or flourish.

In summary, though our zeolites formula contains fulvates and humates, they are not as added-to pure type of ingredients, but intrinsic to the ingredients themselves, whereupon those ingredients are subjected to processes and procedures that remove any vector of contamination factors, including ingredient-based contamination (again, part of our cGMP/HACCP compliant and Kosher certified standards), with the finished end-products possessing an intrinsic quality that is not compatible to fungus or bacteria harboring and/or growth. In other words, the concerns for other zeolites products out there that have had problems with and/or potential for problems with bacterial contamination or vectors for bacterial contamination do not apply in any sense to our zeolites product. Remember, Zeotrex® is made under stringent FDA cGMP standards, are HACCP compliant, and fully Kosher certified by a Kashrus agency recognized by the largest Kashrus agencies throughout the Kosher certified world.


4) I heard of a doctor in California who had put a handful of her patients on a popular zeolites product for several months, all the while running blood work on them. The results of her blood samples showed an increase in aluminum levels in all patients. Do you think that the manufacturing process this company used somehow caused a breakdown in the alumina-silicate bond, allowing free floating aluminum to be absorbed by the body?

Concerning the higher blood levels of aluminum in the blood after taking a zeolites product could be normal with a 'colloidal' mineral produced product. Of course I'm talking of a 'true' colloid, not a colloidal enhanced product. Aluminum has gotten a very bad rap because of the high amounts of the crystalo-metallic varieties that have gotten into the ecology, food supplies, etc., because of its being a byproduct of industrial manufacture. However, the colloidal form of aluminum does not possess the toxicity or heavy metal type qualities of its crystalo-metallic counterpart.

Two points to consider. First, aluminum is the most abundant mineral element in the earth's crust. Nature must have a reason for that being the case. Cucumbers are one of the richest sources of aluminum (colloidal of course) known in the botanical kingdom, and I've never heard of anyone having an aluminum-based toxic reaction to cucumbers. Second, the nerves of the body naturally are high in aluminum compounds. Again, there's a reason nature intended for this. I believe the following may give some insight into this reason.

It has been observed that tornados high electricity storms tend to travel along high tension power line grids and follow fence lines. The high tension power lines are almost all aluminum, and most fences for a number of years are alloyed with aluminum compounds. It appears that aluminum may be natures preferred conductor and trapper of energy currents. I'm no electrician or electronics specialist, but when I passed this by some friends, who both have extensive schooling and training in electrics and electronics, they agreed that there is something to this observation. I'm just saying the body may, on some level, also be subject to these aluminum/energy factors.

The problem with aluminum toxicity is when the aluminum crystallizes in the body (usually as salts of aluminum) and goes from its healthy form to an unhealthy crystalo-metallic form, and from there becomes a free-radical conductor, oxidating salt of aluminum, etc. Remember, 'form' is the key here and for all minerals.

The upshot being, the high levels of aluminum that show up in the blood when taking zeolites minerals could either be the displacing that mineral colloids are known for, i.e. the colloidal form displacing the metallic/salt form (which the body will do if given the right mineral form to do so and has the vitality reserves to carry it off) with the metallic/salt form dumped into the blood to be eventually discarded through the urinary system, or that may have already taken place and the levels of colloid of aluminum have finally been met and the residual colloids are being one of the qualities that colloids are known for, acting like water soluble compounds, wherein what is not used is simply put into the blood stream and eventually flushed out of the urinary system.


5) In non fibrous Clinoptilolite based zeolites, the alumina-silicates are inert in the human body correct?

That's correct! Such forms of alumina-silicates are considered to be akin to rocks, clay, inert metalics (like chrome on the bumper of a vehicle) and the like, which are inert and cannot interact with biological systems. This is where the nano-colloidalizing technology of the Pureodine process comes in when producing Zeotrex. Everything that the zeolites products are about is primarily based on colloidal chemistry. In fact, colloidal chemistry is at the root of these products. The Pureodine proces removes the inert zeolite impurities while clarifying out and keeping the zeolite colloids in the finished solution. Best of all the process we use actually transforms the inherent electrical valence of the zeolites colloids which further enhances their colloidal properties, including their cleansing qualities.

Like the humic shale sources of liquid trace mineral products, those that are mined from deep underground are much more pure and unpolluted than those that are just underneath surface scrapes and the like, so it is with the zeolites. Even so, both minerals (humic shale deposits and zeolites deposits), which are actually mined in the same exact areas, only at differing strata and drifts, still need the light negatively charged colloidals to be removed (extracted) and transformed into their true colloidal form. In the case of zeolites, this extracting allows the cages of the zeolites colloids to open up and expand.